Title | An open access pilot freely sharing cancer genomic data from participants in Texas. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Becnel, LB, Pereira, S, Drummond, JA, Gingras, M-C, Covington, KR, Kovar, CL, Doddapaneni, H, Hu, J, Muzny, DM, McGuire, AL, Wheeler, DA, Gibbs, RA |
Journal | Sci Data |
Volume | 3 |
Pagination | 160010 |
Date Published | 2016 Feb 16 |
ISSN | 2052-4463 |
Keywords | Access to Information, Biological Specimen Banks, Databases, Genetic, DNA, Neoplasm, Genome, Human, Humans, Information Dissemination, Pancreatic Neoplasms, Texas |
Abstract | Genomic data sharing in cancer has been restricted to aggregate or controlled-access initiatives to protect the privacy of research participants. By limiting access to these data, it has been argued that the autonomy of individuals who decide to participate in data sharing efforts has been superseded and the utility of the data as research and educational tools reduced. In a pilot Open Access (OA) project from the CPRIT-funded Texas Cancer Research Biobank, many Texas cancer patients were willing to openly share genomic data from tumor and normal matched pair specimens. For the first time, genetic data from 7 human cancer cases with matched normal are freely available without requirement for data use agreements nor any major restriction except that end users cannot attempt to re-identify the participants (http://txcrb.org/open.html). |
DOI | 10.1038/sdata.2016.10 |
Alternate Journal | Sci Data |
PubMed ID | 26882539 |
PubMed Central ID | PMC4755126 |
Grant List | P30 CA125123 / CA / NCI NIH HHS / United States U54 HG003273 / HG / NHGRI NIH HHS / United States |
An open access pilot freely sharing cancer genomic data from participants in Texas.
Similar Publications
Deep sequencing of candidate genes identified 14 variants associated with smoking abstinence in an ethnically diverse sample. Sci Rep. 2024;14(1):6385. | .
FAIR Header Reference genome: a TRUSTworthy standard. Brief Bioinform. 2024;25(3). | .
Gut Microbiota and Blood Metabolites Related to Fiber Intake and Type 2 Diabetes. Circ Res. 2024;134(7):842-854. | .