Title | Androgen receptor CAG repeat polymorphism in males of six non-human primate species. |
Publication Type | Journal Article |
Year of Publication | 2012 |
Authors | Mubiru, JN, Cavazos, N, Hemmat, P, Garcia-Forey, M, Shade, RE, Rogers, J |
Journal | J Med Primatol |
Volume | 41 |
Issue | 1 |
Pagination | 67-70 |
Date Published | 2012 Feb |
ISSN | 1600-0684 |
Keywords | Animals, DNA, Male, Pan troglodytes, Polymerase Chain Reaction, Polymorphism, Genetic, Primates, Receptors, Androgen, Trinucleotide Repeats |
Abstract | BACKGROUND: Androgen receptor [CAG](n) microsatellite has been linked to human diseases.METHODS: Six non-human primates were genotyped for the [CAG](n) microsatellite.RESULTS: Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic.CONCLUSIONS: Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases. |
DOI | 10.1111/j.1600-0684.2011.00517.x |
Alternate Journal | J Med Primatol |
PubMed ID | 21978295 |
PubMed Central ID | PMC3479659 |
Grant List | K01 RR025161 / RR / NCRR NIH HHS / United States K01RR025161-01 / RR / NCRR NIH HHS / United States RR013556 / RR / NCRR NIH HHS / United States C06 RR013556 / RR / NCRR NIH HHS / United States K01 OD010973 / OD / NIH HHS / United States P51 RR0139986 / RR / NCRR NIH HHS / United States P51 RR013986 / RR / NCRR NIH HHS / United States |
Androgen receptor CAG repeat polymorphism in males of six non-human primate species.
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